fmoc gly gly gly oh Search Results


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Chem Impex International resin
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Chem Impex International fmoc gly gly gly oh
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Chem Impex International fmoc l propargylglycine pra
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Biosynth Carbosynth fmoc gly oh
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Chem Impex International fmoc tle oh
Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) <t>2-azidoethanamine,</t> <t>DIEA,DMF,</t> r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, <t>Fmoc-Leu-OH,</t> DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.
Fmoc Tle Oh, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International fmoc l cyclopropylglycine
Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) <t>2-azidoethanamine,</t> <t>DIEA,DMF,</t> r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, <t>Fmoc-Leu-OH,</t> DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.
Fmoc L Cyclopropylglycine, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International fmoc d propargylglycine
Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) <t>2-azidoethanamine,</t> <t>DIEA,DMF,</t> r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, <t>Fmoc-Leu-OH,</t> DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.
Fmoc D Propargylglycine, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International fmoc n methylglycine
Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) <t>2-azidoethanamine,</t> <t>DIEA,DMF,</t> r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, <t>Fmoc-Leu-OH,</t> DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.
Fmoc N Methylglycine, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International inc fmoc l
Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) <t>2-azidoethanamine,</t> <t>DIEA,DMF,</t> r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, <t>Fmoc-Leu-OH,</t> DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.
Inc Fmoc L, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International dipeptide glycylglycine
Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) <t>2-azidoethanamine,</t> <t>DIEA,DMF,</t> r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, <t>Fmoc-Leu-OH,</t> DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.
Dipeptide Glycylglycine, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Santa Cruz Biotechnology fmoc gly hmb oh
Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) <t>2-azidoethanamine,</t> <t>DIEA,DMF,</t> r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, <t>Fmoc-Leu-OH,</t> DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.
Fmoc Gly Hmb Oh, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chem Impex International fmoc proprogly oh
Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) <t>2-azidoethanamine,</t> <t>DIEA,DMF,</t> r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, <t>Fmoc-Leu-OH,</t> DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.
Fmoc Proprogly Oh, supplied by Chem Impex International, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) 2-azidoethanamine, DIEA,DMF, r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, Fmoc-Leu-OH, DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.

Journal: European journal of medicinal chemistry

Article Title: Enhanced tumor retention of NTSR1-targeted agents by employing a hydrophilic cysteine cathepsin inhibitor

doi: 10.1016/j.ejmech.2019.05.068

Figure Lengend Snippet: Synthetic Procedures for 1a and 1ba aReagents and conditions: (a) (i) EDCI, NHS, DMF, 0°C, 2-3h (ii) 2-azidoethanamine, DIEA,DMF, r.t., overnight; (b) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, Fmoc-Leu-OH, DIEA, DMF, r.t., 2h; (c) (i) 20% piperidine in DMF, r.t., 30min; (ii) COMU, (+/−)-trans-oxirane-2,3-dicarboxylic acid, DMF, DIEA, r.t., overnight; (c) (i) 20% piperidine in DMF, r.t., 30min; succinic anhydride, TEA, DMF, 50°C, overnight; (e) 90% TFA in DCM, r.t., 2h.

Article Snippet: Fluorenylmethyloxycarbonyl (Fmoc)-protected natural amino acids, Fmoc-Tle-OH, Fmoc-Gly(Propargyl)-OH and N,N-diisopropylethylamine (DIEA) were purchased from Chem-Impex International. (+/−)-Trans-oxirane-2,3-dicarboxylic acid, Europium(III) chloride ( nat EuCl 3 ), copper(II) sulfate (CuSO 4 ), 1-butanol, ascorbic acid, triethylamine (TEA), ethylenediaminetetraacetic acid (EDTA), N-hydroxysuccinimide (NHS), Brij®35, and E-64 were obtained from Sigma-Aldrich.

Techniques: